Resources - Gene Therapy Review

A readable but in-depth review of the current status of gene
therapy appears in the current JOURNAL OF THE PHYSICIANS
ASSOCIATION FOR AIDS CARE (formerly PAACNOTES), dated March
1994. It summarizes the work of the nine U.S. biotechnology
companies currently developing one or more gene-therapy
products for treatment or prevention of HIV infection or
AIDS. The author is Henry E. Chang, Director of Research and
Development at Shared Medical Research Foundation, Tarzana,
California.

The companies are: * Applied Immune Sciences, Inc.; * Avigen;
* Cell Genesys, Inc.; * CellPro, Inc.; * Genetic Therapy,
Inc.; * Immusol, Inc.; * Targeted Genetics Corporation; *
Viagene, Inc.; and * Vical, Inc. Sixteen different potential
products are listed; about a third of them are now in human
trials.

A copy of the March 1994 JOURNAL OF THE PHYSICIANS
ASSOCIATION FOR AIDS CARE, which also has major articles on
interleukins (such as IL-2 and IL-12), and on the testing and
treatment of syphilis, is available for $10 from: PAAC
Publishing, Inc., 101 West Grand Avenue, Suite 200, Chicago,
IL 60610, phone 312/222-1326.