Protease Inhibitor Failures: Call for Information

A Web site for both users and prescribers of protease inhibitors has been set up to collect reports of failures of these drugs.

"We are collecting stories from people who have failed protease inhibitors, or who have had unusual responses to the drugs. 'Unusual responses' would include the following:

"* People whose viral loads did not change after starting combination therapy. This includes people who eventually saw decreases, but only after more than two months on therapy.

"* People whose viral loads decreased in response to treatment, but who experienced a rebound in viral load within the first six months of therapy.

"* People whose viral loads INCREASED when they started therapy.

"* People whose viral loads remained high but whose T-cell counts seemed to increase anyway.

"Users who wish to report serious side effects are also welcome to report their experiences, although this is not a focus of this project.

"For more information, contact Rick Loftus, 415/695-3818, Rick_Loftus@quickmail.ucsf.edu."

The Web address for this project is: (website no longer available).